Tlymphocyte subsets in homosexual men from Copenhagen
- 1 August 1984
- journal article
- research article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 14 (4), 301-305
- https://doi.org/10.1111/j.1365-2362.1984.tb01185.x
Abstract
Screening of sixty-six asymptomatic homosexual men from Copenhagen revealed significantly lower Leu-3a/Leu-2a ratios as compared to controls. Ten (15%) of the homosexuals had a ratio ≤ 1·0. The low Leu-3a/Leu-2a ratios were the result of an increase in the absolute number of Leu-2a cells. Homosexuals with many partners and those who had been sexual partners of patients with the acquired immuno-deficiency syndrome (AIDS) had significantly lower ratios than those without these features. Cytomegalovirus was isolated from urine and/or sputum of 15% and this was associated with a Leu-3a/Leu-2a ratio ≤ 1·0. The observed immunological abnormalities could either represent latent infection with the putative AIDS agent or alternatively be caused by repeated infections and/or exposure to allogenic spermatocytes or lymphocytes.Keywords
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