The Effect of Somatic Mutation on Antibody Affinitya
- 1 December 1983
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 418 (1 Immune N), 171-176
- https://doi.org/10.1111/j.1749-6632.1983.tb18064.x
Abstract
No abstract availableThis publication has 8 references indexed in Scilit:
- Clusters of point mutations are found exclusively around rearranged antibody variable genes.Proceedings of the National Academy of Sciences, 1983
- Somatic diversification is required to generate the V kappa genes of MOPC 511 and MOPC 167 myeloma proteins.Proceedings of the National Academy of Sciences, 1981
- Antibody diversity: Somatic hypermutation of rearranged VH genesCell, 1981
- A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibodyCell, 1981
- Somatic mutation of immunoglobulin light-chain variable-region genesCell, 1981
- IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterpartsNature, 1981
- An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JHCell, 1980
- Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.Proceedings of the National Academy of Sciences, 1979