Hair as a biopsy material V. Hair metal as an index of hepatic metal in rats: copper and zinc
Open Access
- 1 March 1978
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 31 (3), 477-480
- https://doi.org/10.1093/ajcn/31.3.477
Abstract
Hair copper in 500 day-old adult rats was found to correlate directly with copper in whole liver (P < 0.001) and the subcellular liver nuclear (P < 0.022), and cytosol fractions (P < 0.001). An inverse correlation was found between copper in liver microsomes and plasma cholesterol (P < 0.044). Similar data analysis for zinc showed no significant correlations (P > 0.05). The determination of copper in hair may be useful for assessing total liver copper content in human beings. Copper in liver microsomes may participate in the control of plasma cholesterol.This publication has 18 references indexed in Scilit:
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