An autoradiographic study of the projection of visual cortical area 1 to the thalamus, pretectum and superior colliculus of the rabbit

Abstract

The projections of visual cortical area 1 (vl) to the thalamus, pretectum and superior colliculus of the rabbit have been studied by Giolli and Guthrie (1967, 1971) using the Nauta and Fink-Heimer methods to determine the course and distribution of degenerating nerve fibers. The present study represents a reinvestigation of these same projections utilizing the tracing method of autoradiography. An injection of ³H leucine was produced within a small region of vl in each of 18 adult albino rabbits, and the brains were subsequently processed for autoradiography by the method of Cowan et al. (1972). The results have confirmed the observations of Giolli and Guthrie (1967, 71) (1) By showing that vl of the rabbit projects to the thalamic reticular nucleus, the ventral lateral geniculate nucleus, the dorsal lateral geniculate nucleus; the pulvinar, the anterior and posterior pretectal nuclei and the superior colliculus and (2) by showing that a particular retinotopic organization is present in each of these projections. However, unlike Giolli and Guthrie (1967, 1971), the present autoradiographic study has further revealed (1) that both the ventrolateral and the posterior thalamic nuclei receive inputs from vl and (2) that the nucleus of the optic tract is not innervated by axons originating from vl.