A Model For Predicting Diastereoselectivity In Yeast Reductions
- 1 January 1987
- journal article
- review article
- Published by Taylor & Francis in Biocatalysis
- Vol. 1 (2), 117-127
- https://doi.org/10.3109/10242428709040136
Abstract
The preparation of chiral synthons by reduction of prochiral ketones catalysed by baker's yeast and the use of redesigned substrates for such reductions is reviewed. A working model for the diastereoselective reduction of α-substituted β-dicarbonyl compounds is discussed.Keywords
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