Kinetic, equilibrium, and spectroscopic studies on dealkylation ("aging") of alkyl organophosphonyl acetylcholinesterase. Electrostatic control of enzyme topography.
Open Access
- 1 August 1986
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 261 (23), 10646-10652
- https://doi.org/10.1016/s0021-9258(18)67434-4
Abstract
No abstract availableThis publication has 43 references indexed in Scilit:
- Flexibility of the molecular forms of acetylcholinesterase measured with steady-state and time-correlated fluorescence polarization spectroscopyBiochemistry, 1985
- Activation of acetylcholinesterase by monovalent (sodium and potassium) and divalent (calcium and magnesium) cationsBiochemistry, 1984
- Novel pyrene-containing organophosphates as fluorescent probes for studying aging-induced conformational changes in organophosphate-inhibited acetylcholinesteraseBiochemistry, 1982
- Electrostatic control of enzyme reactions: effect of ionic strength on the pKa of an essential acidic group on glucose oxidaseBiochemistry, 1981
- Kinetics of association between bisquaternary ammonium ligands and acetylcholinesterase. Evidence for two conformational states of the enzyme from stopped-flow measurements of fluorescenceBiochemistry, 1979
- A Correlation between the Biological Activity of Alkyltrimethylammonium Ions and Their Mode of Interaction with AcetylcholinesteraseJournal of the American Chemical Society, 1965
- Molecular structural effects produced in proteins by reaction with succinic anhydrideBiochimica et Biophysica Acta, 1958
- Benzyl Tosylates. IV. Halogen Substituent Effects1Journal of the American Chemical Society, 1958
- Benzyl Tosylates. II. The Application of the Hammett Equation to the Rates of their SolvolysisJournal of the American Chemical Society, 1953
- Small-Ring Compounds. VIII. Some Nucleophilic Displacement Reactions of Cyclopropyl, Cyclobutyl, Cyclopentyl and Cyclohexyl p-Toluenesulfonates and HalidesJournal of the American Chemical Society, 1951