CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS

Abstract

1. Artificial carbohydrate-protein antigens containing the azobenzylglycosides of glucose and glucuronic acid give rise in rabbits to antibodies which are distinct and immunologically specific. 2. The artificial antigen containing glucuronic acid reacts in high dilutions in antipneumococcus horse sera Types II, III, and VIII. The chemical basis for this serological activity is discussed.