ACTOMYOSIN FORMATION BY ESTROGEN ACTION

Abstract

The actomyosin concn. and the adenosine-triphosphatase activity were studied after castration and subsequent estrogen admn. in virgin female rabbits. Following ovariectomy the contractile actomyosin system of the uterus and the adenosine-triphosphatase activity decrease. Admn. of estrogen initiates a recovery toward the situation existing in estrus by causing an increase in the actomyosin concn. and also an increase in the adenosine-triphosphatase activity. These data can be correlated with changes in uterine contractility observed by physiologists after ovariectomy and after in vivo action of estrogen in the ovariectomized animal.