A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474
Open Access
- 1 June 1971
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 25 (2), 270-275
- https://doi.org/10.1038/bjc.1971.33
Abstract
An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described. Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens. The particular advantage of this drug is the low incidence of troublesome side effects.Keywords
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