A STUDY OF ETHYLHYDROCUPREIN (OPTOCHIN) IN THE TREATMENT OF ACUTE LOBAR PNEUMONIA

Abstract

HISTORICAL The valuable studies of Morgenroth and his co-workers¹ on the chemotherapy of the quinin alkaloids have shown that ethylhydrocuprein (optochin) has a specific bactericidal effect on the pneumococcus in vitro, and that this compound exerts a protective and curative action in animals experimentally infected with virulent strains of that micro-organism. The specific germicidal action of ethylhydrocuprein on the pneumococcus