The Effect of Bicarbonate, PCO2and pH on Serum Calcium Fractions
- 1 January 1971
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 27 (2), 145-150
- https://doi.org/10.3109/00365517109080201
Abstract
The problem whether bicarbonate and PCO2 have specific effects on serum calcium fractions has been studied by ultrafiltration and spectro-photometric methods. The results show that around 0.1 mmol Ca/1 normal serum is complexed to bicarbonate. The effects of pH and temperature on protein-binding of calcium were the same in the presence and absence of bicarbonate. The increase in protein-binding was linear between pH 7 and 8 and averaged 20 per cent of total calcium irrespective the way the pH changes were produced.Keywords
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