CONVERSION OF L-GULONOLACTONE TO L-ASCORBIC ACID; PROPERTIES OF THE MICROSOMAL ENZYME IN RAT LIVER
- 1 August 1960
- journal article
- letter
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 48 (2), 313-315
- https://doi.org/10.1093/oxfordjournals.jbchem.a127175
Abstract
The enzymic reaction was accelerated by alpha, alpha[image]-dipyridyl, versene, 8-hydroxyquinoline, but not by lycorine or diethylbarbiturate. Under anaerobic condition only 2, 6-dichlorophenol indophenol among 5 dyes tested was effective as electron acceptor. Of 12 sugar lactones L-gulono-,L-galactono,D-lyxono-,D-manno-, and D-arabinolactones were utilized as the substrate in the descending order of reaction rate.This publication has 2 references indexed in Scilit:
- Biological synthesis of l-ascorbic acid in animal tissues: conversion of l-gulonolactone into l-ascorbic acidBiochemical Journal, 1960
- On a lipid cofactor involved in the conversion of l-gulonolactone into l-ascorbic acidArchives of Biochemistry and Biophysics, 1960