Antibiotic Combinations

Abstract

THERE is a paucity of useful data from which the therapeutic effectiveness of combinations of antibiotics can be compared with that of their individual components. This may be accounted for, in large measure, by the great difficulties in obtaining adequately controlled and reliable clinical data from the treatment of patients. Attempts have, therefore, been made in this laboratory to approach the problem by assaying and comparing in the same subjects the antibacterial action of blood after administration of antibiotics in the same doses singly and in pairs. Reports of the results of studies of two pairs of antibiotics have already . . .