Susceptibility of Gram-Positive Cocci to Various Antibiotics, Including Cefotaxime, Moxalactam, and N -Formimidoyl Thienamycin

Abstract

The activities of cefotaxime, moxalactam, MK 0787 ( N -formimidoyl thienamycin), ampicillin, oxacillin, vancomycin, and clindamycin were compared against gram-positive cocci. MK 0787 was the most active and moxalactam was the least active of these drugs, except against methicillin-resistant Staphylococcus aureus , where vancomycin was most active, and penicillin-resistant pneumococci, where cefotaxime was more active.