Abstract
When a frog''s sartorius was immersed in a pure isotonic Na-salt solution at room temp. for a short time, a reversible contracture appeared on sudden change to a cold Ringer''s solution, or any other cold solution; this contracture was produced by the sudden decrease in temp.[long dash]the stimulus of cold. The height of contracture depended (1) on the difference in temp. and (2) on the special action of the Na-salt solution. The sensitizing or facilitating influence of the Na-salt solutions on the cold stimulation was essentially identical with that on the chemical stimulation.