Computed Tomographic Demonstration of Hepatic Tumor with the Aid of Intravenous lodinated Fat Emulsion

Abstract

Computed tomography showed improved visualization of carcinogen-induced hepatoma in rhesus monkeys following i.v. injection of an experimental contrast material, AG 60-99. Selective opacification of the liver and spleen was accomplished with a dose of .gtoreq. 0.1 ml/kg, a fraction of the dose used in conventional X-ray tomography. This marked reduction was made possible by the improved density resolution of the CT scanner. This may be the 1st organ-specific contrast material intended for use with CT scanners.