PKCα: a versatile key for decoding the cellular calcium toolkit
Open Access
- 7 August 2006
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 174 (4), 521-533
- https://doi.org/10.1083/jcb.200604033
Abstract
Conventional protein kinases C (cPKCs) play an essential role in signal transduction and are believed to integrate both global Ca2+ transients and diacylglycerol signals. We provide evidence that PKCα is a ubiquitous readout sensor for the cellular Ca2+ toolkit, including highly restricted elementary Ca2+ release.Keywords
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