Analysis of Virus-Specific CD4+T Cells during Long-Term Gammaherpesvirus Infection
Open Access
- 15 August 2001
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 75 (16), 7744-7748
- https://doi.org/10.1128/jvi.75.16.7744-7748.2001
Abstract
Major histocompatibility complex class II-mediated antigen presentation after intranasal infection with murine gammaherpesvirus 68 differs in mediastinal lymph nodes and spleen. Evidence that virus-specific CD4+T cells were being stimulated was found as late as 6 to 8 months after infection, and cells specific for the viral gp15067–83and ORF11168–180peptides were maintained as a fairly stable proportion of the total response.Keywords
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