Isolation and structure of a new factor of the vitamin B12 group: guanosine diphosphate factor B
- 1 February 1960
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 74 (2), 382-387
- https://doi.org/10.1042/bj0740382
Abstract
A substance of the vitamin B12 group, identified as guanosine diphosphate factor B, was isolated from cultures of a strain of Nocardia rugosa. Evidence is submitted which indicates that this substance (factor 1) is a guanosine 5[image]-pyrophosphoric ester of factor B, in which ribose is linked to N-9 of guanine. The significance of this compound as a possible intermediate in the biosynthesis of vitamin B12 is discussed.Keywords
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