Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl
- 1 November 2007
- journal article
- Published by Elsevier in Experimental Cell Research
- Vol. 313 (18), 3935-3942
- https://doi.org/10.1016/j.yexcr.2007.08.021
Abstract
No abstract availableKeywords
This publication has 27 references indexed in Scilit:
- Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradationBiochemical Journal, 2006
- Mini ReviewNegative regulation of PTK signalling by Cbl proteinsGrowth Factors, 2005
- Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl)Blood, 2005
- Signal transduction via the stem cell factor receptor/c-KitCellular and Molecular Life Sciences, 2004
- Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptorsNature, 2002
- Src-catalyzed Phosphorylation of c-Cbl Leads to the Interdependent Ubiquitination of Both ProteinsPublished by Elsevier ,2001
- The Evolutionarily Conserved N-terminal Region of Cbl Is Sufficient to Enhance Down-regulation of the Epidermal Growth Factor ReceptorJournal of Biological Chemistry, 2000
- Ligand-induced Ubiquitination of the Epidermal Growth Factor Receptor Involves the Interaction of the c-Cbl RING Finger and UbcH7Journal of Biological Chemistry, 1999
- Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1Nature Genetics, 1996
- The Proto-oncogene Product c-Cbl Becomes Tyrosine Phosphorylated by Stimulation with GM-CSF or Epo and Constitutively Binds to the SH3 Domain of Grb2/Ash in Human Hematopoietic CellsPublished by Elsevier ,1995