Ingested Glucose and Fructose in Serum Lipids in Healthy Men and after Myocardial Infarction

Abstract

In order to determine whether the incorporations, into serum lipids, of dietary fructose and glucose were similar, the generally labeled ¹⁴C isotope of each monosaccharide in 25 g of the carbohydrate was ingested, after a 10-hr fast, by 5 healthy men and by 10 men who had had a myocardial infarct. The specific activity of the serum triglycerides was greater after the ingestion of ¹⁴C-fructose than after ¹⁴C-glucose, in both groups, suggesting that fructose is preferred to glucose by the lipid synthetic pathways in the fasted state. When glucose was given, the specific activity of the serum triglycerides, when compared with control, was greater after a myocardial infarct.