Folate Absorption and Malabsorption
- 18 December 1975
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 293 (25), 1303-1308
- https://doi.org/10.1056/nejm197512182932509
Abstract
FOLATE deficiency, probably the most common vitamin deficiency in this country, often occurs as a complication of gastrointestinal disease or of therapy with certain drugs. Like several other vitamins, folate exists in a variety of natural forms, and the study of folic acid represents a fascinating chapter in medical history. After its basic structure was described in 1945,1 more than a dozen previously identified and seemingly unrelated growth principles or antianemia factors, including Wills's "new hematopoietic principle," observed in 1931, factors R and S and vitamins M, Bc, B10 and B11, were recognized as free . . .Keywords
This publication has 16 references indexed in Scilit:
- Congenital isolated defect of folic acid absorptionThe Journal of Pediatrics, 1973
- Identification of folic acid compounds in rat liverBiochemical and Biophysical Research Communications, 1972
- Synthesis of Hepta-y-l-glutamic Acid by Conventional and Solid-Phase Techniques.The Journal of Organic Chemistry, 1970
- The subcellular localization of pteroyl polyglutamate hydrolase and folate in guinea pig intestinal mucosaBiochimica et Biophysica Acta (BBA) - General Subjects, 1969
- A study of folate absorption and metabolism in man utilizing carbon-14—labeled polyglutamates synthesized by the solid phase methodJCI Insight, 1969
- Absorption of Polyglutamic Folate: Participation of Deconjugating Enzymes of the Intestinal MucosaNew England Journal of Medicine, 1969
- Solid-phase synthesis of polyglutamates of folic acidBiochemistry, 1969
- Absorption and Utilization of Polyglutamyl Forms of Folate in ManBMJ, 1968
- NUTRITIONAL MACROCYTIC ANEMIA, ESPECIALLY IN PREGNANCYThe American Journal of the Medical Sciences, 1946
- Synthesis of a Compound Identical with the L. casei Factor Isolated from LiverScience, 1945