Healing-Promoting Action of Dried Aluminium Hydroxide Gel Evaluated by the Method of Histological Measurements in Acetic Acid Ulcer of Rats

Abstract

The effects of dried aluminium hydroxide gel on the healing of rat acetic acid ulcer were studied in comparison to those of propantheline bromide by the method of histological measurements. Dried aluminium hydroxide gel not only decreased the macroscopic ulcer index and the defective area in the ulcerated region but also increased the decreasing index of exposed ulcer floor and the mucosal regeneration index without affecting the thickness of the ulcer base and the development index of collagen fibers. However, propantheline bromide did not have any beneficial effects.