Segregation Ratios of Mutant Alleles from Wild Populations of Mus musculus

Abstract

Five mutant alleles found in different populations of wild mice were shown to segregate from male heterozygotes in ratios greatly exceeding 50%. This leads to the expectation that they should be common in wild populations. Tests of wild mice from 5 populations additional to those reported previously revealed only 2 additional alleles in 2 populations. It is assumed that other factors oppose the spread of such alleles.