Radiation-Induced Bladder Tumors

Abstract
A recent 25 yr experience with patients treated for carcinoma of the uterine cervix who subsequently had bladder tumors is presented. Of the 3091 patients treated 2674 received radiotherapy and 8 had vesical malignancies of varied histopathological type 6 mo. to 20 yr after irradiation. This incidence rate is 299.9/100,000, which is 57.6 times that of the general female population. Benign radiation reactions of the bladder and the possible etiology of radiation induced bladder cancers are discussed.