Effect of pH and proton buffer on oscillations of ion fluxes in rat erythrocytes
- 1 September 1984
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 143 (2), 369-371
- https://doi.org/10.1111/j.1432-1033.1984.tb08382.x
Abstract
The pH-dependence of ionophore-induced oscillations of transmembrane H+ and K+ fluxes in rat erythrocytes was studied. The oscillations apparently are strongly depressed at pH 6.9 and > 7.3. Proton buffers of different nature (Tris/HCl, Mops and glycylglycine) are shown to effectively inhibit the oscillatory process. The significance of H+ concentration in unstirred layers adjacent to the membrane in the mechanism of oscillations is suggested.This publication has 2 references indexed in Scilit:
- Spontaneous inactivation of the Ca2+-sensitive K+ channels of human red cells at high intracellular Ca2+ activityBiochimica et Biophysica Acta (BBA) - Biomembranes, 1983
- Calcium-induced oscillations in K+ conductance and membrane potential of human erythrocytes mediated by the ionophore A23187Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982