Brain Peptides
- 16 April 1981
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 304 (16), 944-951
- https://doi.org/10.1056/nejm198104163041605
Abstract
Peptide Functions in the Central Nervous SystemBrain Peptides as Neuronal MarkersMost degenerative neurologic disorders are characterized by premature cell death in discrete neuronal populations. In some cases, the cellular components affected can be characterized partly by their functional roles in neuronal systems. Further delineation of the cellular basis of such neurologic disorders may contribute important new information about their pathogeneses. Immunocytochemical characterization of the cell types that are commonly affected in degenerative diseases, together with measurement of regional peptide concentrations, may provide clues to the neuronal specificity (or lack of it) involved in a given disorder. It is . . .Keywords
This publication has 62 references indexed in Scilit:
- Substance P in human cerebrospinal fluidNeurology, 1980
- Immunoreactive β-Endorphin and Adrenocorticotropin in Human Cerebrospinal FluidJournal of Clinical Investigation, 1980
- Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementaNature, 1980
- Hyper-Endorphin Syndrome in a Child with Necrotizing EncephalomyelopathyNew England Journal of Medicine, 1980
- Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's diseaseBrain Research, 1980
- Chemical pathology of Huntington's disease.Annual Review of Pharmacology and Toxicology, 1980
- CholecystokininTrends in Neurosciences, 1980
- Vasoactive intestinal polypeptide (VIP): distribution in normal human brain and in Huntington's diseaseBrain Research, 1979
- Effect of vasoactive intestinal peptide (VIP) and other peptides on cAMP accumulation in rat brainBiochemical Pharmacology, 1978
- Somatostatin in Human Cerebrospinal FluidNew England Journal of Medicine, 1977