The Effects of Local Applications of Acetylcholine to the Acoustic Cortex

Abstract

Application of acetylcholine to the acoustic cortex of cats resulted in a period of depression of electrical activity with decreased response to auditory stimuli, followed by a period of spontaneous acetylcholine discharges with a heightened response to auditory stimuli. Distant responses to auditory stimulation could be obtained. Acetylcholine discharges could be inhibited by repeated auditory stimulation.