The Sterilization of Anti-typhoid Vaccine

Abstract

Our knowledge of the antigens of the typhoid bacillus has recently been enlarged by the investigations of Felix & Pitt (1934). It has been recognized that the Vi antigen, newly established by these workers, is not only a very important factor in immunity, but also apparently a more labile substance than the O antigen hitherto regarded as the portion of the typhoid soma vitally concerned with the production of prophylactic immunity.