Nitrite Promotes Lymphoma Incidence in Rats
- 8 June 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 204 (4397), 1079-1081
- https://doi.org/10.1126/science.451551
Abstract
Rats were exposed to sodium nitrite in food or water at concentrations of 0, 250, 1000, and 2000 parts per million. Lymphoma was increased in all groups fed nitrite; the overall combined incidence was 5.4 percent in 573 control rats and 10.2 percent in 1383 treated rats. The mechanism of cancer induction did not appear to be through the formation of nitrosamines but through a more direct effect of nitrite on the lymphocyte.This publication has 13 references indexed in Scilit:
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