Rabbit Lactate Dehydrogenase Isozymes: Effect of p H on Activity
- 7 April 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3771), 82-83
- https://doi.org/10.1126/science.156.3771.82
Abstract
The ability of lactate dehydrogenase isozyme five from rabbit skeletal muscle to catalyze pyruvate reduction is extremely sensitive to changes of pH within the range of 6.2 to 7.8.The activity of lactate dehydrogenase isozyme one from rabbit heart is virtually unaffected by changes of pH within the same range. Isozyme five is activated by low concentrations of oxalacetate and inhibited by higher concentrations, but other substrates of the citric acid cycle have no effect.This publication has 10 references indexed in Scilit:
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