The Association of Atopy with a Gain-of-Function Mutation in the α Subunit of the Interleukin-4 Receptor
Open Access
- 11 December 1997
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 337 (24), 1720-1725
- https://doi.org/10.1056/nejm199712113372403
Abstract
Atopic diseases are very common, and atopy has a strong genetic predisposition.Keywords
This publication has 42 references indexed in Scilit:
- Regulation of Human IgE SynthesisAnnals of the New York Academy of Sciences, 1996
- Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for AtopyNew England Journal of Medicine, 1995
- HLA‐DR and HLA‐DP genotypes and immunoglobulin E responses to common major allergensClinical and Experimental Allergy, 1994
- Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 ReceptorScience, 1993
- Mutations in the RET proto-oncogene are associated with MEN 2A and FMTCHuman Molecular Genetics, 1993
- House dust mite sensitivity: interaction of genetics and allergen dosageClinical and Experimental Allergy, 1992
- Molecular cloning of a cDNA encoding the human interleukin 4 receptorInternational Immunology, 1990
- DOMINANT INHERITANCE OF ATOPIC IMMUNOGLOBULIN-E RESPONSIVENESSThe Lancet, 1988
- Bronchial hyperresponsiveness in two populations of Australian schoolchildren. III. Effect of exposure to environmental allergensClinical and Experimental Allergy, 1987
- Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.The Journal of Experimental Medicine, 1987