Circadian rhythm of apical Na-channels and Na-transport in rabbit distal colon
- 1 July 1988
- journal article
- conference paper
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 44 (7), 608-610
- https://doi.org/10.1007/bf01953312
Abstract
In vivo and in vitro studies showed that electrogenic sodium transport in rabbit distal colon is modulated by aldosterone. It varies in a circadian rhythm; the external synchronizer is the light-dark cycle. The site of regulation was found to be in the apical membrane of colonic epithelial cells, in which the number of conducting sodium-channels is increased by aldosterone.Keywords
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