Emerging views of dopamine in modulating sleep/wake state from an unlikely source: PD

Abstract
The mesocortical, mesolimbic, and mesostriatal systems are the most conspicuous of central dopaminergic pathways,9 and govern cognitive, emotive, and motor behaviors. Midbrain DA neurons have the potential to modulate normal and pathologic thalamocortical neuron excitability and, by inference, the sleep/wake state, not only through connections with the striatum but also by way of extensive axon collaterals to the …