Acidic fibroblast growth factor stimulates opsin levels in retinal photoreceptor cells in vitro
- 18 July 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 234 (2), 475-479
- https://doi.org/10.1016/0014-5793(88)80141-8
Abstract
It is demonstrated that newborn rat retinal photoreceptor cells can differentiate in monolayer culture, and synthesize de novo photoreceptor-specific proteins such as opsin. When maintained in serum supplemented medium on a laminin substrate, these cells survive for up to 3 weeks. The addition of acidic fibroblast growth factor stimulates an increase in the levels of opsin of 5-10-fold control values, and prolongs cell survival by up to 6 days.Keywords
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