Viroids: Structure and Function
- 31 August 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 205 (4409), 859-866
- https://doi.org/10.1126/science.472709
Abstract
Viroids are nucleic acid species of relatively low molecular weight and unique structure that cause several important diseases of cultivated plants. Similar nucleic acid species may be responsible for certain diseases of animals and humans. Viroids are the smallest known agents of infectious disease. Unlike viral nucleic acids, viroids are not encapsidated. Despite their small size, viroids replicate autonomously in cells of susceptible plant species. Known viroids are single-stranded, covalently closed circular, as well as linear, RNA molecules with extensive regions of intramolecular complementarity; they exist in their native state as highly base-paired rods.Keywords
This publication has 73 references indexed in Scilit:
- Viroid replication is inhibited by α-amanitinNature, 1979
- Conversion of circular viroid molecules to linear strandsFEBS Letters, 1979
- Minor differences between nucleotide sequences of mild and severe strains of potato spindle tuber viroidNature, 1979
- Chromatographic Behaviour of the Viroids of the Exocortis Disease of Citrus and of the Spindle Tuber Disease of PotatoJournal of Phytopathology, 1976
- Detection of DNA complementary to pathogenic viroid RNA in exocortis diseaseNature, 1975
- Association of Two Ribonucleic Acid Species with Cadang-Cadang Disease of Coconut PalmPhytopathology®, 1975
- Viroids: The Smallest Known Agents of Infectious DiseaseAnnual Review of Microbiology, 1974
- Some biological observations on pale fruit, a viroid-incited disease of cucumberEuropean Journal of Plant Pathology, 1974
- Potato Spindle Tuber Virus: A Plant Virus with Properties of a Free Nucleic AcidScience, 1967
- Actinomycin D as a Probe for Nucleic Acid Secondary StructureScience, 1964