Chemiluminescence by human alveolar macrophages: stimulation with heat-killed bacteria or phorobol myristate acetate
- 1 July 1977
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 17 (1), 117-120
- https://doi.org/10.1128/iai.17.1.117-120.1977
Abstract
Unstimulated AM [alveolar macrophages] generated chemiluminescence that remained constant during incubation. Addition of heat-killed Staphylococcus aureus 502A (HKB) or a chemical agent, phorbol myristate acetate, produced high rates of chemiluminescence that were significantly (P < 0.05) increased over unstimulated AM. Phorbol myristate acetate- and HKB-stimulated increases in AM chemiluminescence were completely blocked by enzyme superoxide dismutase. In comparison with unstimulated polymorphonuclear leukocytes, unstimulated AM had significantly (P < 0.05) greater levels of chemiluminescence. After stimulation by phorbol myristate acetate or HKB, AM showed less chemiluminescence than similarly treated polymorphonuclear leukocytes.This publication has 23 references indexed in Scilit:
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