A theoretical method to predict DNA permutation gel electrophoresis from the sequence
- 30 March 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 300 (2), 175-178
- https://doi.org/10.1016/0014-5793(92)80190-r
Abstract
The gel electrophoretic permutation assays of DNA fragments experimentally investigated by different authors were theoretically reproduced using our theoretical model of sequence-dependent curvature. The general pattern of agreement obtained suggests that our method can be usefully adopted as an alternative to the experimental assay, in particular where the lack of a sufficient number of unique restriction sites in the fragment prevents the correct localization of the main bend site.Keywords
This publication has 21 references indexed in Scilit:
- The curvature vector in nucleosomal DNAs and theoretical prediction of nucleosome positioningBiophysical Chemistry, 1991
- Validity of the nearest-neighbor approximation in the evaluation of the electrophoretic manifestations of DNA curvatureBiochemistry, 1990
- Periodical polydeoxynucleotides and DNA curvatureBiochemistry, 1989
- Structural Information in Deterministic Fluctuations of Base Sequences in DNAs. Theoretical Prediction of DNA SuperstructuresPublished by Springer Nature ,1988
- Bent DNA at a yeast autonomously replicating sequenceNature, 1986
- Static and Initiator Protein-Enhanced Bending of DNA at a Replication OriginScience, 1986
- DNA determinants of rRNA synthesis in E. coli: Growth rate dependent regulation, feedback inhibition, upstream activation, antiterminationCell, 1986
- Conformational change in the DNA associated with an unusual promoter mutation in a tRNA operon of SalmonellaCell, 1984
- The locus of sequence-directed and protein-induced DNA bendingNature, 1984
- Anomalous electrophoretic mobility of restriction fragments containing the att regionJournal of Molecular Biology, 1982