Effect of propranolol on the lower oesophageal sphincter in man
- 1 January 1980
- journal article
- Published by Informa Healthcare in Current Medical Research and Opinion
- Vol. 7 (2), 91-95
- https://doi.org/10.1185/03007998009112032
Abstract
The effect of an intravenous dose (2 mg) of propranolol in the lower oesophageal sphincter was studied in 10 human volunteers. A hydraulic-capillary infusion manometric technique was used to measure the lower oesophageal sphincter pressure. A significant increase in sphincter pressure was recorded, together with increased amplitude and duration of oesophageal peristaltic activity. This study confirms the presence of specific beta-receptors in the lower oesophageal sphincter.Keywords
This publication has 15 references indexed in Scilit:
- Improved Infusion System for Intraluminal Esophageal ManometryGastroenterology, 1977
- Pharmacology of the Esophageal Motor FunctionAnnual Review of Pharmacology, 1975
- Action of oral metoclopramide on the gastrooesophageal junction in manGut, 1973
- Action of gastrin on the lower oesophageal sphincter in manGut, 1969
- The effect of atropine on the gastroesophageal sphincterCanadian Journal of Physiology and Pharmacology, 1968