Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors
- 1 February 2010
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 20 (3), 1106-1108
- https://doi.org/10.1016/j.bmcl.2009.12.025
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetesEmerging Drugs, 2008
- In silico prediction of brain and CSF permeation of small molecules using PLS regression modelsEuropean Journal of Medicinal Chemistry, 2008
- 1,3-Disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitorsBioorganic & Medicinal Chemistry Letters, 2007
- The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetesThe Lancet, 2006
- Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 DiabetesJournal of Medicinal Chemistry, 2005
- Aminomethylpyrimidines as novel DPP-IV inhibitors: A 105-fold activity increase by optimization of aromatic substituentsBioorganic & Medicinal Chemistry Letters, 2004
- 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic PropertiesJournal of Medicinal Chemistry, 2003
- Simple, Highly Active Palladium Catalysts for Ketone and Malonate Arylation: Dissecting the Importance of Chelation and Steric HindranceJournal of the American Chemical Society, 1999
- The antimalarials quinacrine and chloroquine induce weak lysosomal storage of sulphated glycosaminoglycans in cell culture and in vivoToxicology, 1996
- Beiträge zur Chemie der heterocyclischen pseudobasischen Aminocarbinole, XXIV 1) Herstellung von 2‐Oxo‐1.2.3.4.6.7‐hexahydro‐11 b H ‐benzo[ a ]chinolizinenEuropean Journal of Inorganic Chemistry, 1962