Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea
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Open Access
- 3 January 2008
- journal article
- Published by Springer Nature in Malaria Journal
- Vol. 7 (1), 1
- https://doi.org/10.1186/1475-2875-7-1
Abstract
The protection afforded by human erythrocyte polymorphisms against the malaria parasite, Plasmodium falciparum, has been proposed to be due to reduced ability of the parasite to invade or develop in erythrocytes. If this were the case, variable levels of parasitaemia and rates of seroconversion to infected-erythrocyte variant surface antigens (VSA) should be seen in different host genotypes.Keywords
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