AN ANTIHISTAMINE‐LIKE SUBSTANCE (OR SUBSTANCES) IN EXTRACTS PREPARED FROM HUMAN TISSUES
Open Access
- 1 December 1963
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 21 (3), 419-426
- https://doi.org/10.1111/j.1476-5381.1963.tb02009.x
Abstract
A method for the extraction of an antihistamine-like substance (or substances) from human tissues is described. The method has demonstrated the presence of this active principle(s) in a large variety of human tissues, so far without exception. The substance(s) has a wide range of activity in antagonizing the in vitro effects of histamine, 5-hydroxytryptamine and bradykinin and the Schultz-Dale reaction on the guinea-pig ileum and rat uterus preparations.Keywords
This publication has 10 references indexed in Scilit:
- ANTIHISTAMINE ACTIVITY IN EXTRACTS OF HORSE EOSINOPHILSBritish Journal of Pharmacology and Chemotherapy, 1962
- The presence in normal human urine of a substance or substances antagonizing histamine, 5-hydroxytryptamine, and acetylcholine (preliminary report).1962
- THE PRESENCE IN NORMAL HUMAN URINE OF A SUBSTANCE OR SUBSTANCES ANTAGONIZING HISTAMINE, 5-HYDROXYTRYPTAMINE, AND ACETYLCHOLINE (PRELIMINARY REPORT)Canadian Journal of Biochemistry and Physiology, 1962
- Antihistamine activity of extracts prepared from buffy-coat layer of horse blood and from oak gallThe Journal of Physiology, 1960
- Studies with Eosinophil Leucocytcs Isolatcd from the Blood of the HorseBritish Journal of Haematology, 1960
- The properties of the isolated granules from blood eosinophiles.1953
- [Demonstration of a hitherto unknown antihistaminic agent formed in the body (resistin)].1951
- Antihistaminic effect of eosinophil leukocytesCellular and Molecular Life Sciences, 1950