Gamma Globulin: Unmasking of Hidden Antigenic Sites on Light Chains
- 10 July 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3628), 167-168
- https://doi.org/10.1126/science.145.3628.167
Abstract
Normal light (L) chains cleaved from normal pooled human gamma globulin contain immunologic determinants not overtly present in the native unreduced molecule. These hidden determinants are shared with Bence Jones proteins. Similarly, one of two Bence Jones proteins contained immunologic determinants which were not overtly present on the autologous serum myeloma protein.Keywords
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