An End in the Beginning
- 5 June 1998
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 280 (5369), 1548-1549
- https://doi.org/10.1126/science.280.5369.1548
Abstract
All organisms can keep time, with an internal clock that has a period of just about 24 hours. In his commentary, Dunlap outlines recent research ( including a research article and report in this issue by Gekakis and Darlington) that give us a first molecular glimpse of how the protein components of this clock interact.Keywords
This publication has 18 references indexed in Scilit:
- The Genetic Basis of the Circadian Clock: Identification of frq and FRQ as Clock Components in NeurosporaPublished by Wiley ,2007
- Role of the CLOCK Protein in the Mammalian Circadian MechanismScience, 1998
- The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factorsProceedings of the National Academy of Sciences, 1998
- A Circadian Enhancer Mediates PER-Dependent mRNA Cycling in Drosophila melanogasterMolecular and Cellular Biology, 1997
- cDNA Cloning and Tissue-Specific Expression of a Novel Basic Helix–Loop–Helix/PAS Protein (BMAL1) and Identification of Alternatively Spliced Variants with Alternative Translation Initiation Site UsageBiochemical and Biophysical Research Communications, 1997
- Conceptual translation of timeless reveals alternative initiating methionines in DrosophilaNucleic Acids Research, 1997
- Circadian Clock Neurons in the Silkmoth Antheraea pernyi: Novel Mechanisms of Period Protein RegulationNeuron, 1996
- Circadian Rhythms in Cultured Mammalian RetinaScience, 1996
- Temporal phosphorylation of the Drosophila period protein.Proceedings of the National Academy of Sciences, 1994
- PAS is a dimerization domain common to Drosophila Period and several transcription factorsNature, 1993