High diastereoselectivity in the reaction of α-aminonitriles bearing an (S)-(+)-2-methoxymethylpyrrolidine group with Grignard reagents

Abstract
(S)-(+)-2-Methoxymethylpyrrolidine induces high diastereoselectivities (80% diastereoisomeric excess) in the reaction of α-aminonitriles with Grignard reagents.