Abstract
The concentration of triglyceride in the adrenal gland, measured by the method of Van Handel and Zilversmit, was found to be 2.2-3.2 mg/100 mg fresh tissue in the normal rat; this value increased to 3.5-4.8 mg/100 mg tissue 24-48 hr. after hypophysectomy. Injection of 0.1-10 U of adrenocorticotropin in the rat 24-48 hr. after hypophysectomy caused a 20-45% reduction in adrenal triglyceride concentration. This effect was apparent 3 hr. after injection and persisted for at least 6 hr.