Synthesis of 2-epi-Amphidinolide E: An Unexpected and Highly Selective C(2) Inversion during an Esterification Reaction
- 23 December 2006
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 9 (2), 307-310
- https://doi.org/10.1021/ol0628098
Abstract
A synthesis of 2-epi-amphidinolide E (1) has been accomplished via an unexpected and highly diastereoselective C(2) stereochemical inversion during the modified Yamaguchi esterification of alcohol 4b and Fe(CO)3-complexed dienoic acid 7.Keywords
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