LYSIS OF ANTIBODY COATED CHICKEN ERYTHROCYTES BY A NON-LYMPHOCYTE PIG-BLOOD LEUKOCYTE

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 11 (1), 13-20
Abstract
Antibody-dependent cellular-cytotoxicity (ADCC) was studied by the 51Cr release test after a 18 h incubation of non-immune porcine blood leukocytes with labeled chicken erythrocytes sensitized with pig antibodies. ADCC was inhibited by incubation of leukocytes with aggregated immunoglobulins. Pig lymphocytes were inactive, while non-lymphocyte pig leukocytes are effector cells even at low effector:target ratios.