Triaryl(Oxy)Phosphine Dibromide- A Convenient Reagent for the Preparation ofS-Arylthioinosines andN6, 5′-Disubstituted Adenosine Derivatives from Inosine
- 1 June 1988
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 7 (3), 375-383
- https://doi.org/10.1080/07328318808068717
Abstract
Inosine isopropylidene 1 reacts with triphenylphosphine/phosphite dibromide and thiophenol to give 5′-bromo-S-phenylthioinosine 5 which is a versatile precursor for 5′,N 6-disubstituted adenosine derivatives.This publication has 3 references indexed in Scilit:
- Halo sugar nucleosides. 6. Synthesis of some 5'-deoxy-5'-iodo and 4',5'-unsaturated purine nucleosidesThe Journal of Organic Chemistry, 1979
- Preparation of the enantiomeric forms of 9-(5-deoxy-.alpha.-threo-pent-4-enofuranosyl)adenine and 9-(3,5-dideoxy-.beta.-D-glycero-pent-4-enofuranosyl)adenine and in vitro antileukemic screeningJournal of Medicinal Chemistry, 1979
- Phosphororganische Verbindungen, XVII Reaktionen mit Triphenylphosphin‐dihalogeniden Über den Reaktionsverlauf der Halogenübertragung und Wasserabspaltung mit PhosphorhalogenidenEuropean Journal of Organic Chemistry, 1959