REGULATION OF THE CELL CYCLE BY DIETHYLSTILBESTROL AND PROGESTERONE IN CULTURED ENDOMETRIAL CELLS

Abstract

Cultures of primary explanted rabbit endometrium epithelial cells were a mixture of dividing or cycling (20%) and non-dividing or G0 (80%) cells. The addition of diethylstilbestrol switched most of the G0 cells into the cell cycle and shortened the length of the cell cycle through a shortening of G1 and S. Progesterone had the opposite effects.